AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on October 14, 2008
doi: 10.3174/ajnr.A1225

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CT and MR Imaging of Progressive Dural Involvement by Nephrogenic Systemic Fibrosis

S. Zelaskoa, M. Hollingsheada, M. Castilloa and T.W. Bouldinb

a Department of Radiology, University of North Carolina Hospital, Chapel Hill, NC
b Departments of Pathology and Laboratory Medicine, University of North Carolina Hospital, Chapel Hill, NC


Figure 1
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Fig 1. October 2005. Axial T1-weighted postgadolinium MR imaging examination demonstrates diffuse dural enhancement. Changes in bone marrow are likely secondary to anemia.


Figure 2
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Fig 2. May 2006. Section of dura mater from the right frontal lobe shows fibrosis and blue-staining area of calcification. A multinucleated giant cell (arrow) is in the area of fibrosis next to the focus of calcification (hematoxylin-eosin stain).


Figure 3
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Fig 3. June 2006. Axial noncontrast CT image at the level of the tentorium in brain windows and magnified image at the level of the lateral ventricles in bone windows demonstrate diffuse dural calcification (arrows on magnified image).


Figure 4
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Fig 4. November 2006. Axial T1-weighted postgadolinium MR imaging examination demonstrates progressive thickening and enhancement of the dura.


Figure 5
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Fig 5. March 2008. Axial noncontrast CT image at the level of the tentorium in brain windows and magnified image at the level of the lateral ventricles in bone windows demonstrate progressive dural calcification (arrows on magnified image).