Advanced

AJNR - American Journal of Neuroradiology

Published ahead of print on September 3, 2008
doi: 10.3174/ajnr.A1260

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hu, S.-h. Articles by Xu, Y. Search for Related Content PubMed PubMed Citation Articles by Hu, S.-h. Articles by Xu, Y.

Patterns of Brain Activation during Visually Evoked Sexual Arousal Differ between Homosexual and Heterosexual Men

S.-h. Hu^a, N. Wei^a, Q.-D. Wang^b, L.-q. Yan^c, E.-Q. Wei^d, M.-M. Zhang^b, J.-B. Hu^a, M.-l. Huang^a, W.-h. Zhou^a and Y. Xu^a

^a Department of Mental Health, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
^b Department of Radiology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
^c MD Anderson Cancer Center, Virginia Harris Cockrell Cancer Research Center, University of Texas, Austin, Tex
^d Department of Pharmacology, College of Medicine, Zhejiang University, Hangzhou, China

View larger version (35K): [in this window] [in a new window]   Fig 1. Mean scores of the sexual attractiveness of films showing F-F, F-M, and M-M and the maximal level of evoked sexual arousal (SA) in the 2 groups. In homosexual men, M-M stimuli induce maximal sexual arousal, whereas F-M stimuli are preferred in heterosexual men. Results of 2 independent samples test comparisons (homosexual versus heterosexual) are displayed. Blue indicates homosexual men; green, heterosexual men; the asterisk, P < .001. Error bars equal 1 SD.

View larger version (61K): [in this window] [in a new window]   Fig 2. Images showing brain activation in response to M-M stimuli in the homosexual group compared with the same regions in response to F-M stimuli in the heterosexual group, by 1-sample t test analysis. In each labeled panel of 6 images, the upper rows are from homosexual men and the lower rows are from heterosexual men. Significant activation occurs in the left angular gyrus (x = –42, y = –68, z = 48) (A), left caudate (x = –8, y = 0, z = 24) (B), and right pallidum (x = 14, y = 0, z = 6) (C). The bar shows the range of the t value. Numbers in the bottom row indicate the coordinates of the Montreal Neurological Institute brain.

View larger version (83K): [in this window] [in a new window]   Fig 3. Images showing brain activation in response to F-M stimuli in the heterosexual group compared with the same regions in response to M-M stimuli in the homosexual group, by 1-sample t test analysis. In each labeled panel of 8 images, the upper rows are from homosexual men and the lower rows from heterosexual men. Significant activation occurs in the left lingual gyrus (x = 2, y = –80, z = –2) (A), right lingual gyrus (x = 6, y = –70, z = 2) (B), right hippocampus (x = 20, y = –36, z = –2) (C), and right parahippocampus (x = 16, y = –36, z = –10) (D). The bar shows the range of the t value. Numbers in the bottom row indicate the coordinates of the Montreal Neurological Institute brain.