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AJNR - American Journal of Neuroradiology

Published ahead of print on September 10, 2008
doi: 10.3174/ajnr.A1236

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Endovascular Interventions following Intravenous Thrombolysis May Improve Survival and Recovery in Patients with Acute Ischemic Stroke: A Case-Control Study

T.C. Burns^a, G.J. Rodriguez^a, S. Patel^a, H.M. Hussein^a, A.L. Georgiadis^a, K. Lakshminarayan^a and A.I. Qureshi^a

^a From the Zeenat Quereshi Stroke Research Center, University of Minnesota, Minneapolis, Minn

View larger version (16K): [in this window] [in a new window]   Fig 1. Graph shows the distribution of admission NIHSS scores for patients in each group displayed in a relative-frequency histogram. Black bars indicate patients who received IV rtPA but no endovascular intervention. Gray bars indicate patients who received IV rtPA followed by endovascular intervention. Mean NIHSS scores at admission were not different between the 2 groups (P = .822).

View larger version (16K): [in this window] [in a new window]   Fig 2. Graph shows the distribution of NIHSS scores at follow-up for patients in each group, displayed in a relative-frequency histogram. Black bars indicate patients who received IV rtPA but no endovascular intervention. Gray bars indicate patients who received IV rtPA followed by endovascular intervention. NIHSS scores at follow-up were significantly better in patients who received IV rtPA plus endovascular intervention (P = .037).

View larger version (19K): [in this window] [in a new window]   Fig 3. Changes in NIHSS scores from admission to follow-up for patients, displayed in a relative-frequency histogram. Black bars indicate patients who received IV rtPA but no endovascular intervention. Gray bars indicate patients who received IV rtPA followed by endovascular intervention. Patients who worsened after admission have negative scores (toward the left), whereas patients who improved have positive scores (toward the right). Improvement in NIHSS scores is significantly higher in patients who received IV rtPA plus an endovascular intervention (P = .025).