Published ahead of print on December 13, 2007
doi: 10.3174/ajnr.A0887
Intratumoral Microhemorrhages on T2*-Weighted Gradient-Echo Imaging Helps Differentiate Vestibular Schwannoma From Meningioma
K. Thamburaja,
V.V. Radhakrishnanb,
B. Thomasa,
S. Nairc and
G. Menonc
a Departments of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India
b Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India
c Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India

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Fig 1. A–B, Axial T2- and T1-weighted images, respectively, of left VS show no evidence of hemorrhage (arrow). Note the extension into the IAC (arrowhead). C, Photomicrograph shows the Antoni A (+) and Antoni B (*) components in the VS (H&E x150). D, Axial postcontrast T1-weighted image shows bright enhancement of the tumor with nonenhancing areas (arrow). E, T2*-weighted GRE shows multiple hypointense intratumoral signals suggestive of microhemorrhage. F, Photomicrograph showing discrete and confluent masses of hemosiderin pigments (arrow) in the Schwann cell tumor (Perls stain x150).
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Fig 2. A, T1-weighted postgadolinium axial image shows right CPA meningioma with extension into the adjacent IAC (arrow). B, T1-weighted postgadolinium coronal image shows extension of the tumor into the IAC more clearly (arrow) compared with the contralateral IAC (arrowhead).
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Fig 3. A, Axial T2-weighted TSE image shows the relatively hyperintense meningioma in the right CPA with a broad base against the petrous bone (arrow). Note the vasogenic edema of the adjacent cerebellum and middle cerebellar peduncle (star). B, On axial T1-weighted SE, the tumor is isointense to the brain. C, Postcontrast T1-weighted image at the corresponding level shows intense enhancement of the tumor (arrow). D, Axial T2*-weighted GRE does not show hypointense signals characteristic of microhemorrhage in the tumor (arrow). The tumor matrix appears homogeneous. E, Photomicrograph showing features of a meningioma in which neoplastic cells are displayed in concentric whorls and lobules of varying sizes. These neoplastic cells are supported on a vascularized connective stroma (H&E x150).
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