AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on February 22, 2008
doi: 10.3174/ajnr.A0969

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Tumor-Volume Changes after Radiosurgery for Vestibular Schwannoma: Implications for Follow-Up MR Imaging Protocol

O.W.M. Meijera, E.J. Weijmansb, D.L. Knolc, B.J. Slotmana, F. Barkhofb, W.P. Vandertopd and J.A. Castelijnsb

a Departments of Radiation Oncology, VU University Medical Center, Amsterdam, the Netherlands
b Departments of Radiology, VU University Medical Center, Amsterdam, the Netherlands
c Departments of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands
d Departments of Neurosurgery, VU University Medical Center, Amsterdam, the Netherlands


Figure 1
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Fig 1. Typical sagittal MR imaging section with a vestibular schwannoma.


Figure 2
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Fig 2. The processed image of the MR imaging section in Fig 1 with a contoured tumor.


Figure 3
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Fig 3. Tumor volumes grouped with respect to treatment response. MRI indicates MR imaging.


Figure 4
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Fig 4. A, Tumor volumes at sequential MR images for the 24 tumors initially <2 cm3. B, Tumor volumes at sequential MR images for the 16 tumors initially from 2 to 7 cm3. C, Tumor volumes at sequential MR images for the 5 tumors initially >7 cm3.


Figure 5
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Fig 5. The logarithmic volumetric change of VS after radiosurgery with respect to time. The thick line represents the median natural logarithm of the tumor volumes as a function of time. Lines were smoothed by using a moving-average technique.