AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on March 13, 2008
doi: 10.3174/ajnr.A0959
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Proton MR Spectroscopy in the Evaluation of Cerebral Metabolism in Patients with Fibromyalgia: Comparison with Healthy Controls and Correlation with Symptom Severity

M. Petroua, R.E. Harrisb, B.R. Foerstera, S.A. Mcleanc, A. Send, D.J. Clauwb and P.C. Sundgrena

a Department of Radiology, Division of Neuroradiology, Ann Arbor, Mich
b Department of Internal Medicine, Division of Rheumatology; Ann Arbor, Mich
c Department of Emergency Medicine; Ann Arbor, Mich
d Center for Statistical Consultation and Research, Department of Statistics; University of Michigan, Ann Arbor, Mich


Figure 1
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  		Fig 1. Images illustrating voxel placement at the level of the basal ganglia (A) with corresponding spectra (B) and the centrum semiovale (C), also with corresponding spectra (D).


Figure 2
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  		Fig 2. Graphs showing the distribution of Cho/Cr ratios in the right DLPFC in patients with FM and HC (A) as well as the correlations between Cho/Cr ratios in the right DLPFC and left caudate nucleus for patients and controls (B).


Figure 3
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  		Fig 3. Significant correlations between metabolite ratios and clinical symptoms. Correlations between Cho/Cr ratios in the right DLPFC and clinical pain scores on the visual analog scale (VAS) are shown in A. Correlations between evoked pain thresholds and NAA/Cho ratios in the left insula and left basal ganglia are shown in B and C, respectively.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X