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AJNR - American Journal of Neuroradiology

Published ahead of print on April 3, 2008
doi: 10.3174/ajnr.A0993

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Inclusion or Exclusion of Intratumoral Vessels in Relative Cerebral Blood Volume Characterization in Low-Grade Gliomas: Does It Make a Difference?

G. Brasil Caseiras^a,b, J.S. Thornton^a, T. Yousry^a,b, C. Benton^b, J. Rees^b, A.D. Waldman^c and H.R. Jäger^a,b

^a Lysholm Department of Neuroradiology, University College London, London, United Kingdom
^b Institute of Neurology, University College London, London, United Kingdom
^c Department of Imaging, Charing Cross Hospital, London, United Kingdom

View larger version (52K): [in this window] [in a new window]   Fig 1. T2*-weighted image during maximum arterial signal intensity drop (A) and rCBV map (B) in low-grade OD, demonstrating the position of ROIs used to calculate rCBVmax. Method 1 (open arrowhead, posterior ROI in the left cerebral hemisphere, overlying an intratumoral vessel) and method 2 (closed arrowhead, anterior ROI in the left cerebral hemisphere, lying outside intratumoral vessels). The mean CBV from contralateral normal-appearing white matter (ROI in the right cerebral hemisphere) was used to normalize the data for each method. White circles have been superimposed on the original color-coded ROIs generated by FuncTool.