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AJNR - American Journal of Neuroradiology

Published ahead of print on May 1, 2008
doi: 10.3174/ajnr.A1105

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Optimal Diffusion-Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia

Y.C. Weon^a, J.H. Kim^a, J.S. Lee^b and S.Y. Kim^b

^a Departments of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, Korea
^b Departments of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, Korea

View larger version (112K): [in this window] [in a new window]   Fig 1. A 49-year-old woman (patient 8) with TGA. A, Initial DWIs obtained at 11 hours 15 minutes after the onset of symptoms show no lesion at b = 1000/5 mm, but a subtle bright lesion in the right hippocampal body (arrows) at b = 1000/3 mm, b = 2000/3 mm, and b = 3000/3 mm, with increasing lesion conspicuity by increasing the b-value. B, Follow-up DWIs after 3 days show a much brighter lesion (arrows) in all sequences.

View larger version (109K): [in this window] [in a new window]   Fig 2. A 50-year-old woman (patient 3) with TGA. All initial DWIs (A) obtained at 4 hours 30 minutes after the onset of symptoms and follow-up DWIs (B) after 3 days at b = 1000/5 mm do not show the lesion. Follow-up DWIs at b = 1000/3 mm, b = 2000/3 mm, and b = 3000/3 mm show a bright lesion (arrows) in the right hippocampal body, though the signal intensity-to-noise ratio becomes poor by increasing the b-value.