AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on May 15, 2008
doi: 10.3174/ajnr.A1070
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Dual Antiplatelet Therapy Monitoring for Neurointerventional Procedures Using a Point-of-Care Platelet Function Test: A Single-Center Experience

D.H. Leea,b, A. Aratb, H. Morsib, H. Shaltonib, J.R. Harrisc and M.E. Mawadb

a Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
b Department of Radiology, Baylor College of Medicine, Houston, Tex
c Accumetrics Inc, San Diego, Calif


Figure 1
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  		Fig 1. Distribution of ARU in patients receiving dual antiplatelet therapy. Most patients are within the target inhibition range, <550 ARU (dotted line).


Figure 2
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  		Fig 2. Distribution of values associated with clopidogrel response in patients receiving dual antiplatelet therapy. A, BASE value. B, PRU. C, Percentage inhibition. The working cutoff value is 40% (dotted line).


Figure 3
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  		Fig 3. Variability of PRU according to the duration of dual antiplatelet therapy. CI indicates confidence interval.


Figure 4
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  		Fig 4. Changes in PRUs (A) and percentage inhibition (% inhibition) (B) after an additional clopidogrel loading dose in 10 patients. Results are shown for initial (PRU1 and % inhibition1) and follow-up tests after an additional loading dose of clopidogrel (PRU2 and % inhibition2).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X