AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on April 10, 2008
doi: 10.3174/ajnr.A1068

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Local Intra-Arterial Eptifibatide for Intraoperative Vessel Thrombosis during Aneurysm Coiling

V. Katsaridis, C. Papagiannaki, N. Skoulios, I. Achoulias and D. Peios

From the Neurosurgical Department, Papanikolaou General Hospital, Thessaloniki, Greece


Figure 1
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Fig 1. A, Digital subtraction angiography, right vertebral artery, working projection, showing a broad-based aneurysm of the basilar tip. The distal vertebral and the basilar arteries demonstrate areas of severe stenosis. B, Occlusion of the aneurysm with thrombosis of the distal part of the stent and total occlusion of the left PCA. C, Final result, with recanalization of the stent and of the PCA following the administration of 15-mg eptifibatide on the clot and balloon angioplasty of the stenotic lesions. Note that there are no signs of aneurysm recanalization.


Figure 2
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Fig 2. A, Digital subtraction angiography, left ICA, working projection showing an aneurysm at the bifurcation of the MCA. The aneurysm is wide-necked and incorporates the origin of the temporal branch in its base. The MCA and its branches show signs of severe posthemorrhagic vasospasm. B, Subtotal occlusion of the aneurysm with preservation of the patency of the temporal branch of the MCA. C, Total occlusion of the MCA due to thrombus formation. The microcatheter is still in the aneurysm. D, Final result with total recanalization of the MCA following the administration of 10-mg eptifibatide on the clot. Note that there are no signs of aneurysm recanalization