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AJNR - American Journal of Neuroradiology

Published ahead of print on July 3, 2008
doi: 10.3174/ajnr.A1153

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Role of Recanalization in Acute Stroke Outcome: Rationale for a CT Angiogram-Based "Benefit of Recanalization" Model

E.S. Rosenthal^a, L.H. Schwamm^a, L. Roccatagliata^c, S.B. Coutts^d, A.M. Demchuk^d, P.W. Schaefer^b, R.G. Gonzalez^b, M.D. Hill^d, E.F. Halpern^b and M.H. Lev^b

^a Department of Neurology, Massachusetts General Hospital, Boston, Mass
^b Department of Radiology, Massachusetts General Hospital, Boston, Mass
^c Department of Neuroscience, Ophthalmology, and Genetics, University of Genoa, Genoa, Italy
^d Department of Clinical Neurosciences, Foothills Hospital, University of Calgary, Calgary, Alberta, Canada

View larger version (51K): [in this window] [in a new window]   Fig 1. Multivariate predictors of outcome in patients with complete recanalization and in patients with incomplete recanalization. The model R2 represents the sum of the incremental R2 values of each selection variable added to the model in stepwise fashion. Of note, the presence of leptomeningeal collaterals had an inverse correlation with mRS, though the reported R2 is positive by definition. In addition, whereas both models remained strongly significant after step 3, variables added in step 3 of each model did not significantly increase the overall predictive capacity (R2) of each model beyond that provided for by the initial 2 variables.