AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on May 22, 2008
doi: 10.3174/ajnr.A1114

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Retropharyngeal Lymph Node Metastasis From Esthesioneuroblastoma: A Review of the Therapeutic and Prognostic Implications

L.V. Zollingera, R.H. Wiggins, IIIb, R.S. Corneliusc and C.D. Phillipsd

a Departments of Radiology; Head and Neck Neuroradiology, University of Utah School of Medicine, Salt Lake City, Ut
b Radiology, Otolaryngology, Head and Neck Surgery, and Biomedical Informatics; Head and Neck Neuroradiology, University of Utah School of Medicine, Salt Lake City, Ut
c Department of Radiology, Section of Neuroradiology, University of Cincinnati Medical Center, Cincinnati, Ohio
d Department of Radiology, Section of Neuroradiology, University of Virginia School of Medicine, Charlottesville, Va


Figure 1
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Fig 1. A, Axial T2 MR imaging at the level of the hard palate shows an enlarged right lateral retropharyngeal lymph node (asterisk). B, Coronal T1 postgadolinium scan with fat saturation through the nasal cavity and orbits shows the large esthesioneuroblastoma with extensive orbital and intracranial invasion. The arrow shows a peritumoral cyst.


Figure 2
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Fig 2. A relatively low magnification (100X) view of a retropharyngeal lymph node containing nests of tumor cells on the left half of the field.


Figure 3
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Fig 3. A, Axial contrast-enhanced CT through the level of the mandible demonstrates bilateral enhancing masses within the submandibular glands. B, Axial contrast-enhanced image of the skull base at the level of the hard palate shows an enhancing right lateral retropharyngeal lymph node (asterisk) and 2 enhancing left superficial parotid masses.


Figure 4
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Fig 4. A, Axial noncontrast CT image at the level just caudal to the hard palate demonstrates an enlarged right lateral retropharyngeal lymph node (asterisk) causing mass effect on the adjacent parapharyngeal fat. B, Axial noncontrast CT image of the skull base at the level of the torus tubarius showing the postsurgical changes within the nasal cavity and nasopharynx from craniofacial resection.


Figure 5
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Fig 5. A, Axial T1 image with fat saturation obtained at the skull base demonstrating an enhancing left lateral retropharyngeal lymph node. B, Axial noncontrast CT image showing the percutaneous CT-guided biopsy results of the suspect left retropharyngeal lymph node.