AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on July 3, 2008
doi: 10.3174/ajnr.A1188

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Is There a Way to Predict Outcome in (Near) Term Neonates with Hypoxic-Ischemic Encephalopathy Based on MR Imaging?

L. Liauwa, J. van der Gronda, A.A. van den Berg-Huysmansa, L.A.E.M. Laanb, M.A. van Buchema and G. van Wezel-Meijlerc

a Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
b Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands
c Department of Neonatology, Leiden University Medical Center, Leiden, the Netherlands


Figure 1
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Fig 1. T1-weighted image (TR/TE, 550/14; signals acquired, 2; matrix, 205/256; section thickness, 5 mm; section gap, 0.5 mm; FOV, 16 cm) of a neonate from the HIE group (HIE grade 2) imaged at 3 days of age. The image shows higher SI in the posterolateral putamen (arrow) than in the posterior limb of the internal capsule (arrowhead) and abnormal SI in the lateral thalami. The neonate was born at a gestational age of 40+4 weeks, the mother underwent an emergency cesarean delivery for fetal distress, and the neonate was resuscitated. The Apgar score was 0–4–5 (at 1, 5, and 10 minutes). At 5 years of age, this child has an abnormal development (outcome group 3).


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Fig 2. T1-weighted image (TR/TE, 550/14; signals acquired, 2; matrix, 205/256; section thickness, 5 mm; section gap, 0.5 mm; FOV, 16 cm) of a neonate from the control group imaged at 2 days of age. The image shows higher SI in the posterior limb of the internal capsule (arrowhead) than in the posterolateral putamen (arrow). The child was a term-born neonate with a simple lumbar meningocele. At the age of 5 years, this child has a normal development (outcome group 1).