AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on October 22, 2008
doi: 10.3174/ajnr.A1280
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MR Imaging Findings in 56 Patients with Wernicke Encephalopathy: Nonalcoholics May Differ from Alcoholics

G. Zuccolia, D. Santa Cruzd, M. Bertolinib, A. Rovirae, M. Galluccif, C. Carollog and N. Pipitonec

a Department of Radiology, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
b Department of Physics, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
c Department of Internal Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
d Department of Radiology, Hospital Italiano, Buenos Aires, Argentina
e Magnetic Resonance Unit, Hospital Vall d'Hebron, Barcelona, Spain
f University Hospital S. Salvatore, L'Aquila, Italy
g University Hospital, Padova, Italy


Figure 1
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  		Fig 1. A 54-year-old woman with leukemia, changes in consciousness, and ataxia. FLAIR axial images (11,000/140/2 [TR/TE/NEX]). A, The prepositus hypoglossal nuclei show symmetric high-signal-intensity alterations (arrows). B, The medial vestibular nuclei show symmetric hyperintense lesions (arrows). C, Symmetric high-signal-intensity alterations in the facial nuclei (arrows) are detected. Subtle signal-intensity alterations in the abducens nuclei are seen (arrowheads). D, The tectum of the midbrain and the periaqueductal gray matter shows signal-intensity alterations (arrow). E, The mamillary bodies (arrows) show signal-intensity alterations. F, Note signal-intensity alterations (arrows) of the medial thalami and periventricular region of the third ventricle.


Figure 2
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  		Fig 2. A 54-year-old woman with a history of food refusal had changes in consciousness. FLAIR coronal images (11,000/140/2 [TR/TE/NEX]). A, Signal-intensity alterations with different intensity patterns are seen in the thalami (arrows). Diffuse signal-intensity alterations of the frontal cortex (arrowheads) are present. B, Note signal-intensity alterations in the mamillary bodies (arrows), periventricular region of the third ventricle (empty arrows), and brain cortex (arrowheads).


Figure 3
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  		Fig 3. A 47-year-old woman with a history of alcohol abuse presented with ataxia, changes in consciousness, and ocular abnormalities. A, FLAIR axial image (9000/114/1 [TR/TE/NEX]). No signal-intensity alteration are seen at the mamillary body level (arrows). B, T1-weighted axial image (551/14/2 [TR/TE/NEX]). Contrast enhancement is seen in the mamillary bodies (arrows).





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X