AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on October 14, 2008
doi: 10.3174/ajnr.A1329
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Reduced Gray Matter Volume in the Frontotemporal Cortex of Patients with Early Subacute Sclerosing Panencephalitis

K. Aydina, O. Okurd, B. Tatlib, S.G. Sarwarc, C. Ozturkd and C. Dilbere

a Department of Neuroradiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
b Department of Pediatric Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
c Department of Radiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
d Institute of Biomedical Engineering, Bogazici University, Bebek, Istanbul, Turkey
e Department of Pediatrics, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey


Figure 1
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  		Fig 1. Axial FLAIR (TR = 9800 ms, TE = 110 ms, NEX = 2) image of a patient with stage 2 disease reveals normal findings.


Figure 2
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  		Fig 2. Statistical parametric maps demonstrating the structural difference in gray matter volumes. Significant gray matter volume decrease (P < .05, corrected) is overlaid in color on the normalized T1-weighted images of a healthy control subject. Only clusters of voxels consisting of at least 20 voxels are displayed. The color scale shows the range of Z values. It shows the reduced gray matter volumes in bilateral medial temporal regions, including the amygdala, cingulate gyri, and right inferior frontal gyrus.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X