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AJNR - American Journal of Neuroradiology

Published ahead of print on January 8, 2009
doi: 10.3174/ajnr.A1399

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Abnormal White Matter Signal on MR Imaging Is Related to Abnormal Tissue Microstructure

J.L.Y. Cheong^a,b,c, D.K. Thompson^d, H.X. Wang^d, R.W. Hunt^a,b,e, P.J. Anderson^a,f, T.E. Inder^a,b,e,g and L.W. Doyle^a,b,c

^a Victorian Infant Brain Studies, Murdoch Children's Research Institute, Parkville, Australia
^b Royal Women's Hospital Melbourne, Parkville, Australia
^c Department of Obstetrics and Gynecology, Parkville, Australia
^d University of Melbourne, Howard Florey Institute, Parkville, Australia
^e Royal Children's Hospital, Melbourne, Australia
^f Department of Psychology, University of Melbourne, Melbourne, Australia
^g St. Louis Children's Hospital, Washington University, St Louis, Mo

View larger version (83K): [in this window] [in a new window]   Fig 1. A, Axial line scan images obtained at the level just above the superior margins of the lateral ventricles. The 4 images used to determine the regions of interest were the following: 1) FA (top left), 2) relative anisotropy (top right), 3) ADC (bottom left), and 4) diffusion-weighted (bottom right). Six regions of interest were located in the following regions: frontal white matter, sensorimotor white matter, and occipital white matter. B, Axial line scan image obtained at the level of the basal ganglia and PLIC. The 4 images used to determine the regions of interest were the following: 1) FA (top left), 2) relative anisotropy (top right), 3) ADC (bottom left), and 4) diffusion-weighted (bottom right). Six regions of interest were located in the following regions: frontal white matter, middle third of the PLICs, and occipital white matter.