Advanced

AJNR - American Journal of Neuroradiology

Published ahead of print on January 22, 2009
doi: 10.3174/ajnr.A1424

This Article Free to Access Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Denby, C.E. Articles by Mayes, A.R. Search for Related Content PubMed PubMed Citation Articles by Denby, C.E. Articles by Mayes, A.R.

The Frequency and Extent of Mammillary Body Atrophy Associated with Surgical Removal of a Colloid Cyst

C.E. Denby^a, S.D. Vann^b, D. Tsivilis^a, J.P. Aggleton^b, D. Montaldi^a, N. Roberts^c and A.R. Mayes^a

^a School of Psychological Sciences, Manchester, England
^b School of Psychology, Cardiff University, Cardiff, Wales
^c Magnetic Resonance and Image Analysis Research Centre, Liverpool, England

View larger version (127K): [in this window] [in a new window]   Fig 1. The stereologic procedure for measuring the mammillary bodies. A and B, Mammillary body location and detailed structure. C, Placement of the stereologic grid. D, Method of stereologic point counting. The mammillary body volume estimate is contained within the area indicated by the white arrows.

View larger version (107K): [in this window] [in a new window]   Fig 2. Comparison of the resolution of the 1 x 1 x 1 mm isotropic volume scan (A) with the 0.8-mm thin-section volume scan (B) in a patient with relatively normal mammillary body volumes. The 2 sections are taken from neighboring sections around the central region of the patient's mammillary bodies and show the higher resolution of the 0.8-mm scan and the resultant benefit for the identification of the mammillary body landmarks.

View larger version (19K): [in this window] [in a new window]   Fig 3. Distribution of intracranial normalized control and patient mammillary body volumes.

View larger version (24K): [in this window] [in a new window]   Fig 4. Cumulative classification of intracranial normalized patient mammillary body volumes according to the percentage of cases with atrophy below the control mean by using z-scores (1-sample t tests, 1-tailed).

View larger version (160K): [in this window] [in a new window]   Fig 5. The range of atrophy across our study population. A, Healthy mammillary bodies from a control subject. B, Mild asymmetry in a patient with a colloid cyst. C and D, Severe mammillary body atrophy in the patient group. R indicates right; L, left.