AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on January 8, 2009
doi: 10.3174/ajnr.A1431
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Differences of Clinical Manifestations According to the Patterns of Brain Lesions in Acute Encephalopathy with Reduced Diffusion in the Bilateral Hemispheres

A. Okumuraa,b, H. Kidokoroc, T. Tsujid, M. Suzukid, T. Kubotac, T. Katod, M. Komatsub, T. Shonob, F. Hayakawad, T. Shimizua and T. Morishimae

a Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan
b Department of Pediatrics, Urayasu Ichikawa Municipal Hospital, Chiba, Japan
c Department of Pediatrics, Anjo Kosei Hospital, Anjo, Japan
d Department of Pediatrics, Okazaki City Hospital, Okazaki, Japan
e Department of Pediatrics, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan


Figure 1
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  		Fig 1. MR imaging findings of a patient with diffuse lesions. Top: The day after the onset, T1-weighted (T1WI) images show mild thickening of the cortex and T2-weighted (T2WI) images reveal mildly increased intensities in the cortex of the bilateral frontal lobes. Reduced diffusivity is observed in the bilateral frontal and occipital regions on DWIs (frontal occipital lesions). Bottom: Five days after the onset, T1WI and T2WI images demonstrate marked edematous changes in the entire cortex. Reduced diffusivity is observed in the entire subcortical white matter on DWIs.


Figure 2
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  		Fig 2. MR imaging findings of a patient with central sparing lesions. Top: Two days after the onset, no abnormalities are observed. Bottom: Four days after the onset, T1-weighted (T1WI) images show unclear gray-white matter differentiation in the bilateral frontal regions. T2-weighted (T2WI) images reveal diffuse thickening of the cortex and increased signal intensities in the bilateral caudate nuclei. Reduced diffusivity is observed in the bilateral frontal and parietooccipital regions on DWIs.





Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X