Published ahead of print on February 4, 2009
doi: 10.3174/ajnr.A1480
Evolution of Unilateral Perinatal Arterial Ischemic Stroke on Conventional and Diffusion-Weighted MR Imaging
J. Dudinka,c,d,
E. Mercurib,
L. Al-Nakiba,
P. Govaertc,
S.J. Counsella,d,
M.A. Rutherforda,b,d and
F.M. Cowana,b,d
a Imaging Sciences Department, Medical Research Council Clinical Sciences Centre, Imperial College London, UK
b Department of Pediatrics, Medical Research Council Clinical Sciences Centre, Imperial College London, UK
c Neonatal Intensive Care Unit, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
d Hammersmith/St. Mary's Comprehensive Biomedical Research Centre, London, UK

View larger version (12K):
[in this window]
[in a new window]
|
Fig 1. Graph shows the SI score (y-axis) of the infarcted cortex on T1-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.
| |

View larger version (12K):
[in this window]
[in a new window]
|
Fig 2. Graph shows the SI score (y-axis) of the infarcted white matter (WM) on T1-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.
| |

View larger version (75K):
[in this window]
[in a new window]
|
Fig 3. Images show the temporal evolution of a right-sided main branch MCA territory infarction (patient 1) on T1-weighted images (top row) and T2-weighted images (bottom row) obtained on days 2, 5, 12, 42, and 75 postdelivery.
| |

View larger version (12K):
[in this window]
[in a new window]
|
Fig 4. Graph shows the SI score (y-axis) of the infarcted cortex on T2-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.
| |

View larger version (12K):
[in this window]
[in a new window]
|
Fig 5. Graph shows the SI score (y-axis) of the infarcted white matter (WM) on T2-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.
| |

View larger version (88K):
[in this window]
[in a new window]
|
Fig 6. T2-weighted images of a patient with an infarction within the anterior MCA branch territory on day 5 (patient 15) show high SI changes within the ipsilateral thalamus (arrow, A) and the ipsilateral brain stem (arrow, B).
| |

View larger version (17K):
[in this window]
[in a new window]
|
Fig 7. Graph shows the evolution of changes in stroke border recognition and contrast in white matter (WM) by using a composite of the scoring system.
| |

View larger version (10K):
[in this window]
[in a new window]
|
Fig 8. Graph shows the SI score (y-axis) of the infarcted tissue on DWIs from each postnatal day (x-axis). d indicates day. HSI indicates high SI.
| |

View larger version (102K):
[in this window]
[in a new window]
|
Fig 9. Graph shows DWIs of a patient with an infarction within the PCA territory, showing severe HSI on day 3 (A) and mild-to-moderate HSI on day 10 (B).
| |