AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on February 4, 2009
doi: 10.3174/ajnr.A1480

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Evolution of Unilateral Perinatal Arterial Ischemic Stroke on Conventional and Diffusion-Weighted MR Imaging

J. Dudinka,c,d, E. Mercurib, L. Al-Nakiba, P. Govaertc, S.J. Counsella,d, M.A. Rutherforda,b,d and F.M. Cowana,b,d

a Imaging Sciences Department, Medical Research Council Clinical Sciences Centre, Imperial College London, UK
b Department of Pediatrics, Medical Research Council Clinical Sciences Centre, Imperial College London, UK
c Neonatal Intensive Care Unit, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands
d Hammersmith/St. Mary's Comprehensive Biomedical Research Centre, London, UK


Figure 1
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Fig 1. Graph shows the SI score (y-axis) of the infarcted cortex on T1-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.


Figure 2
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Fig 2. Graph shows the SI score (y-axis) of the infarcted white matter (WM) on T1-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.


Figure 3
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Fig 3. Images show the temporal evolution of a right-sided main branch MCA territory infarction (patient 1) on T1-weighted images (top row) and T2-weighted images (bottom row) obtained on days 2, 5, 12, 42, and 75 postdelivery.


Figure 4
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Fig 4. Graph shows the SI score (y-axis) of the infarcted cortex on T2-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.


Figure 5
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Fig 5. Graph shows the SI score (y-axis) of the infarcted white matter (WM) on T2-weighted MR images from each postnatal day (x-axis). d indicates day; w, week; m, month.


Figure 6
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Fig 6. T2-weighted images of a patient with an infarction within the anterior MCA branch territory on day 5 (patient 15) show high SI changes within the ipsilateral thalamus (arrow, A) and the ipsilateral brain stem (arrow, B).


Figure 7
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Fig 7. Graph shows the evolution of changes in stroke border recognition and contrast in white matter (WM) by using a composite of the scoring system.


Figure 8
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Fig 8. Graph shows the SI score (y-axis) of the infarcted tissue on DWIs from each postnatal day (x-axis). d indicates day. HSI indicates high SI.


Figure 9
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Fig 9. Graph shows DWIs of a patient with an infarction within the PCA territory, showing severe HSI on day 3 (A) and mild-to-moderate HSI on day 10 (B).