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AJNR - American Journal of Neuroradiology

Published ahead of print on March 25, 2009
doi: 10.3174/ajnr.A1543

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Neurovascular Modeling: Small-Batch Manufacturing of Silicone Vascular Replicas

J.Y. Chueh^a, A.K. Wakhloo^a and M.J. Gounis^a

From the Department of Radiology, University of Massachusetts Medical School, Worcester, Mass

View larger version (22K): [in this window] [in a new window]   Fig 1. Virtual cerebrovascular models show ICA siphons with mild (A), medium (B), and severe (C) curvature.

View larger version (104K): [in this window] [in a new window]   Fig 2. The virtual core-shell structure (A) is designed for the preparation of the physical ABS model (B), which contains the CoW (C) as the core. After the silicone is cured, the ABS model (B) is dissolved in xylene, resulting in a transparent CoW silicone replica (D). E, With the same manufacturing process, a representative right ICA siphon is built from patient 18.

View larger version (17K): [in this window] [in a new window]   Fig 3. The S-S curves of Sylgard 184, LIM 6030, and a human MCA from postmortem examination are compared. At low stretch, the elastic property of LIM 6030 is close to that of the MCA from postmortem examination. Short solid line indicates the MCA from a postmortem examination; dark dashed line, LIM 0.49 mm in thickness; light dashed line, LIM 0.52 mm in thickness; dotted line, LIM 0.53 mm in thickness; diamond, Sylgard 0.49 mm in thickness; square, Sylgard 0.53 mm in thickness; triangle, 0.61 mm in thickness.