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FIG 1. Case 1: 20-year-old woman with hippocampal sclerosis.
A, Left hippocampal head shows slight hyperintensity (arrows) relative to normal right hippocampal head on coronal T2-weighted FSE MR image.
B, Axial T2-weighted MR image shows a focal ovoid hyperintensity lesion (white arrows) in the splenium of the corpus callosum. There is a small, less hyperintense area (black arrow) within the lesion, presumably indicating a spared area of the white matter.
C, Sagittal T1-weighted MR image shows a well-defined focal low-signal-intensity lesion (solid arrows) containing a small, central isointense focus (open arrow), which probably corresponds to the less hyperintense area on the T2-weighted image (B).
D, Follow-up MR image, obtained 4 months after withdrawal of dilantin and vigabatrin, shows that the focal lesion in the corpus callosum has disappeared.
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