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FIG 1. MR imaging of transvascular delivery of Feridex and MION in the rat brain.
A, T1-weighted image obtained 24 hours after osmotic BBB disruption and intracarotid administration of Feridex (10 mg Fe/kg) shows enhancement in the right cerebral hemisphere.
B, T1-weighted image 24 hours after administration of MION (10 mg Fe/kg) with BBB disruption. The disrupted right cerebral hemisphere (R) enhances (white) with iron, while the left hemisphere (L) shows the noncontrast-enhanced rat brain.
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