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FIG 5. Patient 6: early-onset GLD.
A–C, Axial T2-weighted images (2800/80/1) at 7 months of age show increased signal intensity in the pyramidal tract (arrows in A–C). Pyramidal tract involvement in children with white matter that has not yet myelinated can be identified by higher than normal high signal intensity of immature white matter on T2-weighted images.
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