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FIG 1. A–C, A, Proton density–weighted section from a subject with extensive WMSH; B, corresponding segmentation section showing different tissue classes (WMSH in black); C, color-coded map of MTR of WMSH (green corresponds to lowest MTR and yellow to highest MTR, shown in the color bar); and D, a sample of periventricular WMSH (black line, defined as those pixels representing the overlap between WMSH and a two-pixel region grown of ventricular space but excluding all partial volumed pixels (see Methods for details)
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