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FIG 1. Dual BASING with PRESS excitation. The two BASING pulses (RFB1 and RFB1) are separated in time by TE = 2 msec. For Cycle 1, the Lac methine quartet is included in the BASING inversion band, whereas for Cycle 2, the BASING center frequency is shifted downfield to exclude all metabolites of interest. The addition of Cycle 1 and Cycle 2 spectra yields the singlets, whereas the subtraction of Cycle 2 from Cycle 1 yields the Lac methyl doublet
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