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FIG 4. Initial and follow-up brain proton MRS studies in a neonate with moderate HIE performed at 4 and 15 days of age, respectively. The peaks of NAA, Cho, and (Cr + PCr) are clearly visible in all the MRS studies. M-Ino is clearly visible in both the initial and follow-up STEAM proton MRS studies, but is only barely seen on the PRESS proton MRS studies.
A, Initial PRESS proton MRS study (2000/135/250) shows an apparent 
-Glx peak at 3.75 ppm.
B, Initial STEAM proton MRS study (2000/24/250) shows a remarkable -Glx peak.
C and D, Follow-up PRESS (2000/135/250) (C) and STEAM (2000/24/250) (D) proton MRS studies show that the height of the -Glx peak at 3.75 ppm is decreased as compared with that obtained on the initial proton MRS studies with both the PRESS and STEAM proton MRS sequences. Other peaks are similar on both the initial and follow-up PRESS and STEAM proton MRS studies. For abbreviations, see figure 1.
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