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FIG 5. Initial and follow-up brain proton MRS studies in a neonate with severe HIE performed at 7 and 14 days of age, respectively. The peaks of Cho and (Cr + PCr) are clearly visible in all the MRS studies. The NAA peak is easily detected on PRESS proton MRS. However, in STEAM proton MRS studies, it is not well defined and is decreased in height. M-Ino is clearly visible on both the initial and follow-up STEAM proton MRS studies, but is only barely seen on the PRESS proton MRS studies.
A, Initial PRESS proton MRS study (2000/135/250) shows a high peak of 
-Glx at 3.75 ppm.
B, Initial STEAM proton MRS study (2000/24/250) shows a remarkable -Glx peak at 3.75 ppm.
C and D, Follow-up PRESS (2000/135/250) (C) and STEAM (2000/24/250) (D) proton MRS studies show that the height of the -Glx peak at 3.75 ppm is decreased compared with that obtained on the initial PRESS and STEAM proton MRS studies. Other peaks are similar on both the initial and follow-up PRESS and STEAM proton MRS studies. For abbreviations, see figure 1.
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