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FIG 2. A, The measured signal versus time for a moderately enhancing region of a recurrent anaplastic astrocytoma. Enhancement of the signal after the bolus arrival is due to the leakage of contrast agent into the extravascular space.
B, The vascular concentration versus time corrected for the leakage of contrast agent into the tissue for the ROI described in A. The corrected rCBV (shaded area) is twice that of normal white matter.
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