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FIG 2. MTR histograms of cortical/subcortical brain regions from MS patients without (continuous line) and with (dotted line) cognitive impairment. Vertical lines represent the MTR values at which the integral of the histogram is 25%, 50%, and 75% of the total (ie, MTR25, MTR50 and MTR75). The histogram of MTR values from the cortical/subcortical brain tissue of impaired patients has a lower peak height and location than that obtained from unimpaired patients. For further details and statistical analysis, see text
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