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FIG 4. MR spectra from the frontal lobes in a patient with BPAD obtained with smaller voxels.
A, Axial T1-weighted localizer image with grid shows dense. White square outlines the area of analysis. Study was obtained with 2D PRESS technique (TE = 135). Note location of individual voxel (arrow), corresponding to spectra in B.
B, Proton spectra from voxel (arrow, A; 1 x 1 x 1.5 cm) show marked elevation of lipids (L). Note that voxel is far away from any fat-containing structure, precluding extraneous contamination. C, choline; Cr, creatine; N, NAA.
C, Proton spectra of individual voxel placed contralateral and in nearly a mirror position to B still show marked elevation of lipids (L). Again, voxel is placed away from fat-containing structures that could conceivably contaminate it. C, choline; Cr, creatine; N, NAA.
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