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FIG 3. 29-year-old man with radiation necrosis (verified by stereotactic biopsy) who had undergone subtotal tumor resection followed by conventional radiation therapy (60 Gy) and systemic chemotherapy 26 months earlier. Ten months later, tumor recurrence was found, and was treated by subtotal resection and chemotherapy.
A, Contrast-enhanced T1-weighted MR image (690/14/1; section thickness, 5 mm) shows enhanced area (arrow) within surrounding nonenhancing zone of low intensity and mass effect in the left temporal lobe.
B, Radiation necrosis appears as an area of hyovascularity (arrow) on the rCBV map (normalized rCBV ratio, 0.56).
C, Histologic specimen shows avascular areas, consistent with radiation necrosis (hematoxylin-eosin; original magnification x 200).
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