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FIG 1. Statistically significant regions of decreased anisotropy with increasing age. Areas with significant anisotropic decrease with age are shown in blue to blue-white and were identified in the frontal white matter, genu and splenium of the corpus callosum, and parietal and occipital periventricular white matter. Correlation coefficients between RA and age are displayed for each pixel with the scale bar indicating the correlation coefficient from r = -0.55, P < .05 (blue) to the most negative correlation found, P < .0001 (blue-white). (Background is group mean, anatomically standardized, T1-weighted images at four slice locations.)
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