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FIG 2. Statistically significant regions of increased anisotropy with increasing age. Areas of significant diffusion anisotropic increase with age are shown in red-yellow and were identified in the posterior limb of the internal capsules bilaterally and diffusely at the periphery of the brain, notably at the brain-CSF interfaces (most likely artifactual). Correlation coefficients are displayed using a method similar to that in figure 1, with the correlation coefficients from r = .55, P < .05 (red) to the most positive correlation found, r = .90, P < .0001 (yellow). (Background is group mean, anatomically standardized, T1-weighted images at four slice locations.)
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