|
FIG 3. 9-year-old girl thought to have TSC by the referring pediatrician. A calcified lesion was found in the anterior left temporal lobe on CT (not shown).
A, Axial FLAIR MR image shows a high-signal-intensity abnormality in the left temporal lobe that corresponds to the area of calcification on CT scan.
B, Coronal contrast-enhanced T1-weighted image shows no enhancement.
C, Proton MR spectrum of this lesion shows an increase in Cho and a marked reduction in the NA peak, in keeping with a neoplasm rather than a cortical tuber. Review by pediatric neurologists and dermatologists confirmed that TSC was not present clinically.
D and E, Follow-up MR study 6 months later shows the lesion has increased in size on FLAIR image (D), but still does not enhance after contrast administration (E). A diagnosis of low-grade astrocytoma was made on the basis of biopsy findings.
|