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FIG 6. Patient 13.
A and B, Contrast-enhanced gradient-echo images (26/6/1) and spectra (1000/144/1; voxel resolution, 1.0 cm3) acquired the day of radiosurgery (A) and 5 months afterward (B). The radiation target was prescribed to include spectral abnormalities beyond the regions of contrast enhancement. Despite the enlarged treatment field, the 6-month time point shows a large increase in contrast-enhancing volume. Increases in Cho within regions of new contrast enhancement suggest they correspond to recurrent tumor. Also conspicuous is the development of lactate/lipid resonances within the high-dose region. Resection was performed after the final time point shown, which histologically confirmed the increased contrast enhancement as recurrent tumor.
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