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FIG 2. Electron-microscopy preparation of the optic nerve of a 7-day-old rat pup (A) shows no evidence of myelin sheaths or significant structural changes within the oligodendrocytes. Oligodendroglial cells have large nuclei (black arrow). Electron-microscopy preparation of the optic nerve of a 21-day-old rat pup (B) shows myelin sheaths (black arrows) surrounding multiple axons
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