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FIG 4. Signal intensity profiles of the hippocampal allocortex. The profile perpendicular to the cortex (green line, profile in inset a) displays deep dips of low signal intensity at the acellular heavily myelinated alveus (A), the stratum lacunosum (L), the hippocampal sulcus (S), and the unmyelinated densely cellular dentate granule cell layer (D). In the profile along the CA from CA1 to CA4 (curved red line, profile in inset b), signal intensity is inversely related to cellular density. Signal intensity is highest in CA1 (lowest cellular density), decreases to its lowest signal intensity in CA2 (highest cellular density), and then rises progressively toward CA4, as cell density decreases. The blue line fitted to this signal intensity curve approximates an average of the signal intensity in each area. Note that signal intensity in CA4 is lower than that in CA1.
