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FIG 1. Region of interest placement is illustrated on a transverse diffusion anisotropy (A
) image obtained through the level of the basal ganglia in a 1-year-old child. Diffusion anisotropy is computed from a single shot echo-planar diffusion-tensor sequence: 3000/97.4/1 (TR/TE/number of excitations), using four tetrahedrally oriented diffusion gradients (b = 1012.4 s/mm2) and three orthogonally oriented diffusion gradients (b = 337.5 s/mm2). Regions of interest in gray matter are marked as white ellipses, and regions of interest in white matter are marked as black ellipses. Values from the left and right regions of interest were averaged. 1, head of the caudate nucleus; 2, lentiform nucleus; 3, posterior limb of the internal capsule; 4, thalamus; 5, splenium of the corpus callosum.