AJDRAJNR - American Journal of Neuroradiology

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FIG 5. Study animal 16, 6-month implant.

A, Anteroposterior digital subtraction angiogram of the brachiocephalic artery shows a wide-necked 5.5-mm-wide 8.5-mm-high aneurysm (black arrow).

B, Anteroposterior digital subtraction angiogram obtained immediately after embolization with a single complex coil and a single hydrogel device shows dense packing of the aneurysm dome, with persistent flow at the aneurysm neck (straight white arrow).

C, Anteroposterior digital subtraction angiogram obtained 6 months after embolization shows progressive occlusion of the aneurysm cavity, with the neck now occluded (curved white arrow).

D, Hematoxylin and eosin stain; original magnification, x6.8. Coronal section obtained through the aneurysm cavity. The sac is completely filled with hydrogel, which stains as faint, violet-colored, reticular material. A thin layer of organized tissue traverses the neck of the aneurysm (arrow).





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