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FIG 2. AC, 1H-MR spectra (automated stimulated-echo acquisition mode; TR/TM/TE = 3000/13.7/30, LCModel fit) of the right perisplenial lesion (voxel volume 7.28.0 mL; cf voxel position in 1A) in the 4th (A), 8th (B), and 26th (C) week after symptom onset. D, Note the time course indicating partial resolution of the acute inflammatory changes (decrease of Cho, Lac, and Lip), only incomplete recovery of NAA but evolving gliotic reaction (increase of mI). Mean
± SD of unaffected parietal white matter from 15 male HIV-positive subjects (mean age, 40.9; years; range, 2863 years) are given on the left for comparison. Metabolite concentrations were estimated by using LCModel (Provencher S., http://s-provencher.com).