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FIG 2. Images of animal 4.
A, Example of hematoxylin and eosin staining obtained at the level of the balloon. Multiple regions of petechial hemorrhage are indicated by arrows. Petechial hemorrhage is a characteristic of spinal cord contusion.
B, Beta amyloid precursor protein immunostaining of the region shown in A. Amyloid precursor protein is synthesized in neurons in the CNS and peripheral nervous system and is transported to the nerve endings from the cell body. Amyloid precursor protein accumulates when axoplasmic flow is disrupted; it is therefore a sensitive marker of axonal injury. Regions of stain accumulation (arrows) indicate posterior axonal injury.
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