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FIG 3. Images of animal 3.
A, Example of axial view T2-weighted MR image obtained at the level of balloon inflation after the balloon was deflated and removed. The cord displays homogenous signal intensity with no signal intensity change in the dorsal region that shows contrast enhancement in C.
B, Unenhanced T1-weighted MR image obtained in the axial plane at the level of balloon inflation. No abnormal signal intensity is seen in the spinal cord.
C, Contrast-enhanced T1-weighted MR image of the region shown in B. A large region of enhancement is located at the dorsal region of the spinal cord (arrow).
D, Unenhanced sagittal view T1-weighted MR image of the region shown in B. Note that no abnormal signal intensity is seen in the spinal cord.
E, Focal enhancement is observed after the injection of contrast material (arrow).
F, Hematoxylin and eosin staining of the spinal cord shows parenchymal hemorrhage in the peripheral white matter (arrows).
G, Beta amyloid precursor protein immunostaining of the region shown in B highlights well-developed axonal swellings (stain accumulation) in the cross section (arrow).
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