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FIG 2 Case 2, an 80-year-old woman with squamous cell carcinoma of the right side of her tongue.
A, Non-contrast-enhanced CT image at a level II node (arrow) obtained at initial examination; hyperattenuation is not evident.
B, Ninth follow-up sonogram at the level II node obtained 7 months after surgery of the primary tumor (transverse section). Note an enlarged lymph node (arrow) with heterogeneous internal echo.
C, Non-contrast-enhanced CT image at the level II node obtained 7 months after surgery of the primary tumor. Note the hyperattenuation (arrowhead) at a lateral margin of the node (arrow). The size of the node increases and the minimal axial diameter of the node is 9 mm.
D, Contrast-enhanced CT image obtained at the same level and time as that of C. The level II node (arrow) enhances, and hyperattenuation is obscured after the administration of contrast medium.
E, Photomicrograph (stain, hematoxyllin-eosin; original magnification, x2) demonstrates the area of marked keratinization (arrows) within metastatic foci at the marginal portion of the largest one of level II node. The non-contrast-ehnahced CT finding of hyperattenuation appears to be correlated with this marked keratinization within metastatic foci.
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