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FIG 3. Non-Langerhans histocytosis.
A, Histiocytic and chronic inflammatory lesion with extensive fibrosis.
B, Much of the lesion was foamy histiocytes without emperipolesis or giant cells.
C and D, Tumor cells exhibited extensive CD68 (C) but only extremely rare S-100 protein (D) and no CD1a immunoreactivity.
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