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FIG 2. Representative follow-up axial MR images after combined therapy for glioblastoma multiforme in patient 8 (recurrence group).
AC, Gadolinium-enhanced T1-weighted MR image (400/14) (A), FLAIR MR image (10,002/175/22000) (B), and ADC map from DW image (b = 0, 1000 s/mm2) (C) obtained at 7-month follow-up after radiation treatment show a left parietotemporal mass with surrounding T2 prolongation.
DF, Gadolinium-enhanced T1-weighted MR image (400/14) (D), FLAIR MR image (10,002/175/22000 (E), and ADC map from DW image (b = 0, 1000 s/mm2) (F) show a new focus of enhancement in the left basal ganglia at 7-month follow-up after radiation treatment. Further follow-up imaging (not shown) revealed marked progression of enhancement and T2 prolongation. Patient had progressive functional deterioration in clinical course. This patient from the recurrence group exhibited a mean ADC in the enhancing lesion of 1.13 x 10-3 mm/s2, a mean ADC in T2 prolongation of 1.64 x 10-3 mm/s2, and a normalized ADC ratio of the enhancing region of 1.35. X indicates ROI of the enhancing lesion. ROI in T2 prolongation was drawn in a different section.
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