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FIG 1. Correlation analysis of rCBV, K trans, and glioma grade.
A, rCBV and glioma grade were strongly correlated, with Spearman r = 0.817 (P = .0001) and Pearson r = 0.771 (P = .0004). The slope and its gradient are consistent with a strong positive correlation with highly significant P values.
B, A weaker correlation was observed between K trans and glioma grade: Spearman r = 0.234 (P = .046) and Pearson r = 0.277 (P = .017). Although the slope indicates a positive correlation, its gradient is less pronounced, with less significant P values than in A. Furthermore, more overlap is noted in K trans measurements than in the rCBV measurements in A.
C, Relationship between rCBV and Ktrans is characterized by a modest yet statistically significant Spearman rank correlation (r = 0.266; P = .023) and a weak, statistically insignificant Pearson product moment correlation (r = 0.163; P = .168).
D, Receiver operating characteristic curves for rCBV and Ktrans, as estimated from logistic regression. rCBV was a significant predictor of high-grade gliomas with higher sensitivity and specificity than Ktrans.
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