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FIG 4. Focal polymicrogyria in the left frontal lobe. Contiguous, 3-mm-thick, coronal FLAIR fast spin-echo sections (ac) show a deep superior frontal sulcus with a slightly irregular contour and a normal signal intensity of the cortex (arrow). Planar surface-reconstructed view (d) generated from a 1.1-mm-thick, 3D, T1-weighted gradient-echo sequence confirms the distorted anatomy (arrow). Histopathologic sections show loss of neocortical architecture (MAP2 [e]) compared with that of adjacent sixlayered cortex (nematoxylineosin straining [f]).