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FIG 2. Changes in fMR findings before and after tumor resection.
A, Activation maps of BOLD fMRI for the right grasping task (lesion side) and the left grasping task (nonlesion side) before and after tumor resection. Postoperative fMR image 2 days after surgery demonstrated negative BOLD signal changes in the motor cortex on the lesion side. Extended activation in the ipsilateral secondary motor cortex was also observed after surgery. On the postoperative fMR image 22 days after surgery, the negative BOLD signal intensity areas in the motor cortex on the lesion side were decreased in association with an increase in activation areas. By contrast, left-hand grasping activated the motor cortex on the nonlesion side consistently before and after surgery. White arrows indicate the region of interest (a and c, positive signal-intensity changes; b, negative signal-intensity changes).
B, Time course of the BOLD signal changes during the task (blue background).
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