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FIG 2. At 32 weeks’ gestation, US showed decreased cerebellar transverse diameter (<10th percentile) without supratentorial abnormality. MR imaging was performed at 32.5 weeks. Infratentorial biometry was evaluated with MR study at about 28 weeks.
A, T2-weighted coronal section at the level of the thalami shows marked bilateral hyperintensity beneath the thalami just above the hippocampal fissure (arrows). Because of biometric and signal intensity abnormalities, termination of pregnancy was proposed and performed at 34 weeks. NFP confirmed the biometric abnormalities and showed a diffuse gliosis with neuronal necrosis lesions involving the cerebral peduncles, thalami, and hippocampal cortex.
B, Coronal histologic section shows bilateral cavitation (arrows) above both hippocampal fissures.
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