AJDRAJNR - American Journal of Neuroradiology

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FIG 8. AC, Graphs of ADC values and anisotropy index (AI) in the right DLF both rostral and caudal to the transplants. * indicates both animals with unmodified fibroblasts and those with BDNF-expressing fibroblasts were significantly different from normal controls; #, unmodified fibroblasts significantly different from normal controls; ~, BDNF-expressing fibroblasts significantly different from normal controls; +, unmodified fibroblasts significantly different from BDNF-expressing fibroblasts.

A, The tADC values in the right DLF become significantly elevated in white matter adjacent to the grafts, both rostral and caudal. These values become closer to normal as measurements are obtained further from injury site.

B, The lADC values in the right DLF become significantly decreased in white matter adjacent to the grafts compared with those of normal controls, both rostral and caudal. These values become closer to normal as measurements are obtained further from injury site.

C, Anisotropy index (AI) values become significantly elevated (decreased anisotropy) in white matter adjacent to the grafts compared with those in normal controls, both rostral and caudal. These values become closer to normal as measurements are obtained further from injury site.





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